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Alesse (Ovral-L) is a birth control medication (oral contraceptive) produced by the pharmaceutical company Wyeth Pharmaceuticals, Inc. Allesse (Ovral-L) is available under the following brand name: Aviane, Lutera, Orsythia.
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Generic Ovral-L
Alesse (Ovral-L) is a birth control medication (oral contraceptive) produced by the pharmaceutical company Wyeth Pharmaceuticals, Inc. Allesse (Ovral-L) is available under the following brand name: Aviane, Lutera, Orsythia.
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Active ingredients: Levonorgestrel .15 mg + Ethinyl Estradiol .03 mg
Alesse (Ovral-L) is a popular birth control medication (oral contraceptive) produced by the pharmaceutical company Wyeth Pharmaceuticals, Inc. Allesse (Ovral-L) is available under the following brand name: Aviane, Lutera, Orsythia.
Pharmacological action
Alesse (Ovral-L) is a combined monophasic oral birth control drug. Contraceptive effect is associated with the suppression of pituitary secretion of gonadotropin-releasing hormone.
The progestogen component (progestin) Levorgestrel acts at the receptor level without prior metabolic transformation. The estrogen component is ethinyl estradiol. Levorgestrel contributes to the blockade of LH and FSH release from the hypothalamus, inhibition of pituitary gonadotropin-releasing hormone secretion and ovulation development. The contraceptive effect is enhanced by Ethinyl Estradiol. Ethynil estradio maintains high viscosity of cervical mucus making the sperm penetration in the uterus more difficult. Another birth control mechanism consists in changing the lining of the uterus making it less receptive to an embryo.
Indication
Ovral-l (Alesse) is an oral contraceptive used to prevent undesirable pregnancy. In addition to contracetpive effect, Ovral-L has the following beneficial effects on the women health:
Ovral-L mode of administration
You should begin taking Ovral-L (Alesse) in the first day of mentraul cycle taking the pill marked with the correct day of the week. Try to take the medication until the whole pack is finished (21 days) at the same time each day to maintain the constant level of the medication in the blood. The following a 7-days interruption during which a vaginal hemorrhages can occur.
Contraindications:
Ovral-L (Alesse) should be used with caution in patients with liver and gall bladder diseases, depression, ulcerative colitis, uterine cancer, mastitis, tuberculosis, kidney disease, diabetes, diseases of the cardiovascular system, renal dysfunction, varicose veins diseases, otosclerosis, epilepsy, porphyria, epilepsy, bronchial asthma.
Ovral-L (Alesse) should be discontinued in the following cases:
Side effects
Ovral-L is generally well tolerated.
Possible side effects include: nausea, vomiting, headache, breast engorgement, and weight change in libido, mood changes, acyclic bleeding and in some cases - swelling of the eyelids, conjunctivitis, blurred vision, discomfort when wearing contact lenses
In very rary cases Alesse may cause chloasma, hearing loss, generalized pruritus, jaundice, leg cramps, increased frequency of epileptic seizures.
In very rare cases Alesse may cause hypertriglyceridemia, hyperglycemia, impaired glucose tolerance, increased blood pressure, thrombosis and venous thromboembolism, jaundice, skin rashes, changes in the nature of vaginal secretions, candidiasis, fatigue, and diarrhea.
Drug interaction
Barbiturates, some antiepileptic drugs (carbamazepine, phenytoin), sulfonamides, pyrazolone derivatives can enhance the metabolism of Alesse
Reduced contraceptive efficacy can be observed while the appointment of some antimicrobial agents (including with ampicillin, rifampicin, chloramphenicol, neomycin, polymyxin B, sulfonamides, tetracyclines) that is associated with changes in intestinal microflora.
Ovral-L changes the blood levels of anticoagulants
Ovral-L (Alesse) increases the bioavailability and toxicity of tricyclic antidepressants, maprotiline, beta-blockers.
Alesse may change the blood levels of hypoglycemic agents and insulin.
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