Generic Dermovate 0.05% 15gm

Generic Demovare cream

Active ingredient: Clobetasol propionate 

Generic Dermovate is a topical medication which contains clobetasol propionate 500 mcg/g (0.05% w/w). It is available in the form of cream 15 gm. Generic Dermovate is used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. Clobetasol is a very potent (super-high-potency) corticohormon. 

Therapeutic action: Generic Dermovate cream contains clobetasol used to treat a number of skin condition such as eczema, dermatitis, allergies and rash. Clobetasol is a very potent (super-high-potency) corticohormon which helps reduce swelling, itching, and redness in certain skin lesions. Generic Dermovate exerts its effects by a nonspecific anti-inflammatory response. It is considered that this medication can cause vasoconstriction in the blood vessels of the skin and decrease collagen synthesis. Generic Dermovate can be readily absorbed in the body through application in the skin. This effect can be increased with the use of occlusive dressings, or when the skin is inflamed. After it is absorbed, it is well-distributed in the body. It is metabolized as all other corticohormones. 

Indications: Generic Dermovate is indicated for the treatment of psoriasis (excluding widespread plaque psoriasis). It is also used to treat recalcitrant eczemas, and lichen planus. It can also be used to treat discoid lupus erythematosus and other skin conditions which do not respond satisfactorily to less active hormones. 

Generic Dermovate should be applied sparingly to the affected area once or twice daily. Therapy should be discontinued when control of the disease is achieved. First, wash and dry your hands before applying. The affected area should be cleansed and dried. The medication should be applied as a thin film to be gently rubbed in, usually 2-3 times daily or as instructed by your doctor. Avoid covering or wrapping the treated area. Wash your hands after use. Avoid contact with eyes, mouth or mucous membranes. If contact occurs, rinse with plenty of water. Generic Dermovate should not be applied for more than 4 weeks. If your symptoms persist despite treatment after the prescribed time, seek medical help. 

Contraindications:

Generic Dermovate Cream is contraindicated in patients with known hypersensitivity to Clobetasol. It should also not be used in patients with rosacea, acne vulgaris, perioral dermatitis (inflammation of the skin around the mouth), and in viral infections of the skin such as herpes simplex and chickenpox. Generic Dermovate is also contraindicated in skin infections caused by fungi or bacteria, in skin lesion of children less than one year of age and in napkin eruptions. 

Special cautions: Generic Dermovate can be dangerous to be used in psoriasis for a number of reasons including rebound relapses, development of tolerance, risk of generalized pustular psoriasis (psoriasis with pus-filled lesions) and development of local or systemic toxicity due to impaired barrier function of the skin. When dealing with infected skin lesions, appropriate antibiotic treatment should be given. If infection spreads, treatment with Generic Dermovate should be stopped and antibiotics should be given. Bacterial infection can happen when warm, moist occlusive dressings are present; thus the skin should be cleansed before a fresh dressing is applied. Generic Dermovate should not be used for a long period of time. Children and infants should not use this product because of the risk of systemic absorption giving rise to adrenal suppression. Tell your doctor if you are pregnant or lactating before using Generic Dermovate. 

Side effects: Generic Dermovate can cause side effects such as burning, stinging, itching, dryness, or redness at the application site. If these conditions persist or worsen, seek medical help. Generic Dermovate can also cause more serious side effects such as stretch marks, skin thinning/discoloration, acne, extreme/unwanted hair growth, "hair bumps" (folliculitis) and skin infections. If these happen, seek medical help. Watch out for systemic manifestations of hormones such as unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination and vision problems. Also watch out for hypersensitivity reactions such as rash, itching/swelling especially of the face/tongue/throat, severe dizziness, and trouble breathing. 

Drug interaction: Generic Dermovate can interact with drugs such as corticohormones taken by mouth such as prednisone and drugs that lower the immune system such as cyclosporine). 

Storage: Generic Dermovate should be stored at a room temperature not exceeding 30°C. 

Generic Dermovate is classified as Pregnancy Category C (Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.)