Posts Archive for July 2016

Tadacip vs Forzest

Jul.22, 2016

men-strong erectionTadacip and Forzest General introduction:

Tadacip and Forzest are the generic drugs for the famous brand drugs Cialis. The main difference lies in that Tadacip is manufactured by Cipla pharmaceuticals and Forzest is manufactured by Sun pharmaceuticals limited. Both the companies have its origin from India and are one of the leaders in the manufacturing of generic drugs. What does the word generic means? First of all don’t worry about the word generic. The word generic only means that the drug is not the initial patented drug and it was manufactured after the patent period of the original branded drug has got over. The generic drugs Tadacip and Forzest undergo a lot of experiments and trials before been approved by the Food and Drug Administration of the United States and are absolutely efficacious as the original branded drugs.

Problem statement and  how do these drugs acts?

Both the drugs are marketed as a solution for erectile dysfunction. The word erectile dysfunction stands for  the condition in which male is not able to lift his penis during sexual intercourse. This might occur because of a variety of conditions. The basic mechanism behind the appearing of this condition is because of the decrease in the filling of the blood in the blood vessels of the penis. It might occur because of the nerve weakness and also because of the blockage of the blood vessels by atherosclerosis. The presence of erectile dysfunction is nowadays classified as one of the predictors of cardiovascular risk. Erectile dysfunction causes a lot of mental distress and affects the personal life significantly. Both of the drug (Tadacip, Forzest) act by causing the inhibition of phosphodiesterase 5. By means of  inhibiting phosphodiesterase 5, there occurs an increase in the concentration of CGMP. (CGMP stands for Cyclic Guanosine Monophosphate and this represent one of the secondary messengers which are biomolecules responsible for the communications inside the cell) This is because phosphodiesterase 5 breaks down CGMP in the absence of these drugs. The increase in the concentration of CGMP causes dilation of blood vessels. Rather less  an initial sexual stimulation is required, for the formation of nitric oxide.

Tazarotene for large pores

Jul.14, 2016

Actuality of problem and Description of problem

Large pore is a problem in all age groups. There are many reasons why large pores can occur and not all the reasons are correctable with treatment. The pores are normally present in the skin and helps in the drainage of sweat and oil on the surface of skin. Normally these pores are  not visible and this makes our skin looks very beautiful and shiny. In some people, the size of the few pore in the skin becomes larger and thus resulting in a condition known as large pores. This causes a decrease in the beauty of the face and attract attention of everybody towards the problem.

The collagen is the building block of the skin. Collagen are rows of fibers which forms the base for providing the elasticity and texture to the skin. As a person, gets aged out, there occurs degradation of the collagen and thus causes decrease in the support and the enlargement of pores. The excessive exposure to sunlight can also damage the skin and causes enlargement of the pores.

The adolescent age group suffers from the problem of acne because of the block in the drainage of the sebum from the seborrheic gland. The infection and the subsequent inflammation lead to the formation of the blackheads which might precipitate the formation of large pores. (inflammation in the natural response of the body to infection)

In addition to this, some person has large pores because of the familial reason. The characteristics of the person are inherited and expressed in varying extent from the parents by means of genetic transformation. The information passed through these genes might be the reason for the development of large pores.


Why Tazarotene is good for that problem?